In the ever-evolving field of reproductive medicine, technological advancements are crucial in enhancing the efficacy and safety of procedures.
SUPERVITRI™, a novel vitrification device by BPB MEDICA™ represents a significant leap forward in the cryopreservation of oocytes and embryos.
Here’s a glimpse into the comprehensive validation of SUPERVITRI™ and its promising results.
Device overview:
SUPERVITRI™ is designed for the cryopreservation of biological samples with a focus on ease of use, efficiency, and safety. The device boasts a well-structured design that facilitates the vitrification and warming processes with minimal handling, thus reducing the risk of contamination and damage to the samples.
Measurements and Structural Integrity
• The device features optimal dimensions for handling and labelling, ensuring easy identification and minimal risk of sample loss.
• SUPERVITRI™ exhibited robust resistance to liquid nitrogen storage over two weeks without any signs of breakage or leakage.
Cooling and Warming Rates:
• The device demonstrated excellent cooling (-30246°C/min) and warming (+55456°C/min) rates, comparable to existing market-leading systems.
• Using larger volumes of warming solution (4 ml vs. 1 ml) resulted in more consistent warming rates, suggesting an optimized protocol for best results.
Oocyte Survival and Integrity:
• High survival rates were observed in mouse oocytes vitrified and warmed using SUPERVITRI™, with 96.7% survival post-warming.
• Oocytes maintained normal spindle morphology and chromosome distribution, critical for successful fertilization and development.
Embryo Development
• Following vitrification and warming, oocytes, were successfully fertilized via ICSI, with subsequent embryo development rates paralleling those of non-vitrified control groups.
• The results underscore SUPERVITRI’s potential in maintaining oocyte viability and functionality post-cryopreservation.
Conclusion
The validation of SUPERVITRI™ highlights its efficacy in preserving the viability and developmental potential of oocytes through vitrification. These findings mark a significant advancement in cryopreservation technology, offering a reliable and efficient solution for reproductive medicine practitioners.
As we continue to push the boundaries of what’s possible in reproductive health, innovations like SUPERVITRI™ are essential in improving outcomes and offering hope to countless individuals and families.
