First page of a published clinical study confirming the effectiveness of universal embryo warming protocols using SUPERVITRI™

News

23 Jul 2025

New Clinical Study Confirms the Safety and Efficiency of Universal Warming Protocol Using SUPERVITRI™

A large cohort study supports the use of SUPERVITRI™ in universal embryo warming protocols, achieving survival rates from 99.5% to 100%.

We are proud to share the results of a newly published clinical study in Reproductive BioMedicine Online that confirms the effectiveness of the universal warming protocol using our vitrification carrier, SUPERVITRI™.

This large-scale retrospective study, led by Lodovico Parmegiani and colleagues, analysed over 3,000 vitrified human blastocysts warmed using different combinations of commercial vitrification and warming kits, including our SUPERVITRI™.

The study aimed to assess the viability of a universal single-step warming (USSW) method using a 1M non-permeating solute (NPS), independent of the original vitrification kit brand.

Key findings include:

  • Embryo survival rates ranged from 99.5% to 100.0% across all study groups, demonstrating excellent consistency and safety.
  • Clinical pregnancy rates and implantation rates were comparable among all combinations of vitrification and warming kits.
  • The simplified single-step rehydration method (USSW) delivered strong clinical outcomes, offering a faster and more streamlined protocol.
  • SUPERVITRI™, used as one of the vitrification carriers, contributed to these high-performance outcomes, proving its reliability in real-world clinical settings.

The study validates the flexibility and efficiency of SUPERVITRI™ in supporting a universal warming approach, offering IVF laboratories a reliable and cost-effective solution that simplifies workflows and facilitates embryo sharing across clinics.

📖 Read the full study here: https://doi.org/10.1016/j.rbmo.2025.104923

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